The Role of Clinical Pharmacist in Monitoring Drug Therapy in the Cardiovascular and Coronary Care Units in Libya.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- The mortality.
研究概览
简要总结
Assessment of role of clinical pharmacist in decreasing morbidity and mortality among coronary artery disease patients.
详细描述
- Methodology: Follow-up patients from (A to Z) and their risk factors in all phases of disease (CAD) in groups with advised patients to lose weight, decrease smoking, and take medication on time.
Monitoring drugs to CAD by studying its Pharmacodynamic:
Mechanism of action, therapeutic uses [indication], adverse effect and suitable doses, and drug-drug interactions and contraindications
* The study shows the Compare between the patients in (Medical Center Hospital) with and without guidelines of clinical pharmacy. Were managed all by setting a plan with the cardiologist in Libya.
Follow-up was for the one hundred patients in the three groups {Outpatient, Inpatient, and the patients in Cardio Care Unit - CCU}.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 41 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The inclusion criteria were all adults ≥40 years of age, with a diagnosis of CAD.
排除标准
- •exclusion criteria were patients with various comorbidities such as liver or kidney disease; patients intake alcohol, cardiac surgery and refusal to give informed consent.
研究组 & 干预措施
Group II (observation group)
application of clinical pharmacy guidelines and management CAD. Subgroup: 10 outpatient, 25 inpatient, 15 patient in CCU.
干预措施: clinical pharmacy application (Drug)
结局指标
主要结局
The mortality.
时间窗: 18 months, from Jan 2021 to June 2022.
The causes of death are cardiogenic shock, ventricular tachycardia, and myocardial infarction.
Angina pectoris.
时间窗: 18 months, from Jan 2021 to June 2022.
Periodically data collected. \[ex: the measurements of blood pressure, glucose blood serum, and LDL - (and taken the average during the period)\]. The parameters in the research (angina, response to treatment, complication rate, and mortality) - were quantitatively collected, as the results added to the paper contain the number of patients with details of their complications or the cause of death of patients who died). The measuring of FBG level (mg/dl), and (LDL-C) mg/dl - was then performed using a fully automated chemistry analysis instrument by Roche company (Cobas Integra 400 plus). And using specific kits for blood glucose levels (System ID 07-6831-6) and using kits for (LDL-C) (System ID 07-6726-3), Troponin (ng\\ml) was performed by using (Beckman coulter - Access 2). Angina pectoris was more predominant in patients in group (I); vs. in group (II) with a statistically significant difference.
Responsiveness to medications.
时间窗: 18 months, from Jan 2021 to June 2022.
Periodically data collected. \[ex: the measurements of blood pressure, diabetes, lipid profile, and weight - (and taken the average during the period)\]. The parameters in the research (angina, response to treatment, complication rate, and mortality) - were quantitatively collected, as the results added to the paper contain the number of patients with details of their complications or the cause of death of patients who died). Follow-up patients, their clinical state and side effects of medications, Following the number of Hospitalization decreased. Responsiveness to medications was significantly higher among patients from the group (II); compared with a control group (I)
The incidence of complications.
时间窗: 18 months, from Jan 2021 to June 2022.
The complications are noticeable: myocardial infarctions \[Troponin was perpetrated by using by (Beckman coulter)(Access 2) ng\\ml\], cardiac arrhythmias \[by ECG\], cardiogenic shock \[after MI with HF and low BP\], HTN crisis {BP measure, DKA \[high blood glucose with (+) positive Ketones. Data were collected quantitatively, as the results added to the paper contain the number of patients with details of their complications).
次要结局
未报告次要终点
研究者
Asmaa S.H. Alhomri
BCH.PH & pharmaceutical science, Faculty of Pharmacy, Omar Elmokhtar University, Tobruk, Libya.
Beni-Suef University