A clinical trial to study the effects of three desensitizing agents in relieving dentine hypersensitivity.
- Conditions
- Health Condition 1: null- Patients suffering from Dentine hypersensitivity, also those who have gingival recession, abrasion, erosion, abfraction in the cervical third of the tooth.
- Registration Number
- CTRI/2018/05/013903
- Lead Sponsor
- Samuel Raj
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 56
1. Subjects between the age group of 18- 50 years (inclusive),
2. Subjects who complain of hypersensitivity, also those with cervical erosion/abrasion or gingival recession.
3. Subjects who signed the informed consent form.
4. Subjects willing to participate in the study
1. History of allergies or idiosyncrasies to dentifrice ingredients.
2. Gross oral pathology, chronic diseases, advanced periodontal disease, treatment for periodontal disease (within the previous 12 months).
3. Hypersensitive teeth with mobility greater than one as given by Miller.
4. Subjects with teeth that have extensive/defective restorations (including prosthetic crowns), suspected pulpitis, caries, cracked enamel, or those teeth being used as abutments for removable partial dentures are also excluded from the study.
5. Subjects who are current users of anticonvulsants, antihistamines, antidepressants, sedatives, tranquilizers, anti-inflammatory drugs, or daily analgesics.
6. Pregnant or lactating women, individuals who are participating in any other clinical study or who had participated in a desensitizing study, or who used any desensitizing agents within the previous three months.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in dentin hypersensitivity after single direct topical application of these agentsTimepoint: 30 days
- Secondary Outcome Measures
Name Time Method To evaluate the efficacy of dentifrice containing Arginine in reducing dentinal hypersensitivity on single applicationTimepoint: 30 days