Effectiveness of Electro-Acupuncture on treating MDD: a Randomized Controlled Trial

Shanghai Seventh People's Hospital, Shanghai University of TCM0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•Patients with MDD who meet the following criteria will be included:
•1. Between 18 and 75 years of age with no gender-based restriction;
•2. Fulfilling the diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders version 5 (DSM V) for major depressive disorder;
•3. A Hamilton Rating Scale for Depression (HDRS-17) score with a range between 17 to 24 (24 > HDRS-17 >= 17);
•4. Non-aphasic and without severe cognitive disorders, with a Mini-Mental State Examination (MMSE) score (H) greater than 17 (MMSE > 17);
•5. Keenness to participate in the trial and provide written informed consent.

•Subjects reporting any of the following criteria will be excluded:
•1. History or current presence of neuropsychiatric diseases other than depression
•2. Candidates at a high risk of attempting suicide (a score of more than 2 points on the third question (Suicide) of the HDRS-17
•3. People who, prior to the date of screening:
•Have taken antidepressants or any psychotropic drugs;
•Have undergone psychotherapy or Cognitive Behavioral Therapy (CBT);
•Received any kind of therapeutic interventions related to either Western medical practice or
•Traditional Chinese Medicine to alleviate the symptoms of MDD.
•4. Pregnant, lactating, or planning to become pregnant women;
•5. Subjects who have acute inflammation at the planned acupuncture site on the body or any other contraindication to acupuncture;
•6. Candidates afraid of needles in general and reluctant to receive acupuncture in particular;
•7. Patients with bleeding tendency, severe physical disability or other chronic disorders (e.g: chronic alcoholism, drug abuse);
•8. Subject who have already taken part in previous clinical trials where EA treatment was used.

发起方

Shanghai Seventh People's Hospital, Shanghai University of TCM