Socioeconomic Status, Secondary Prevention Activities and Recurrence After a Myocardial Infarction

Completed

• Conditions: Secondary Prevention; Myocardial Infarction; Socioeconomic Status; Stroke; Cardiovascular Disease

• Registration Number: NCT04199663
• Lead Sponsor: Karolinska Institutet

Brief Summary

This is a nationwide cohort study on real-world patients (n≈30,000) surviving a first myocardial infarction (MI) 2006-2013 and alive to attend a routine 1-year follow-up. Associations between Socioeconomic Status (SES) and secondary preventive actions (SPAs) throughout the first year is studied and assessed as possible mechanisms underlying the increased risk of a first recurrent hard cardiocvascular (CV) outcome, recurrent atherosclerotic cardiovascular disease (rASCVD), in patients with low Socioeconomic Status during long-term follow-up (2006-2018).

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Study Start: 2006-01-01
• Primary Completion: 2018-12-31
• Study First Submitted: 2019-12-12
• Study First Submitted QC: 2019-12-12
• Study First Posted: 2019-12-16
• Status Verified: 2020-02
• Last Update Submitted: 2020-02-18
• Last Update Posted: 2020-02-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30191

Inclusion Criteria

• Swedish resident
• Alive and registered in The Swedish Websystem for Enhancement and Development of Evidence based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART)'s secondary prevention subregistry between 1 January 2006 and 31 December 2013 at the 1-year-revisit

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Exclusion Criteria

• Age >76 years at baseline
• Missing data for disposable household income
• History of MI, stroke, coronary artery bypass graft (CABG), or percutaneous coronary intervention (PCI) prior to the index MI
• Not present in initial care registry (RiksHIA)
• Date of index MI before 2004 or missing
• revisit outside 13±2 month window post-MI

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
first recurrent atherosclerotic cardiovascular disease event (rASCVD)	from date of 1-year visit post-MI (baseline) until date of outcome, censoring or study end (2018)	composite outcome including non-fatal MI (I210-I214, I219, I220, I221, I228 or I229) or coronary heart disease death (CHD) (I210-I214, I219, I220, I221, I228, I229, I461 or I469) or fatal or non-fatal ischemic stroke (I630-I635, I638 or I639) according to the International Classification of Diseases 10th edition (ICD-10)