Secondary Prevention Treatments and Activities Post Myocardial Infarction Underlying the Risk of Recurrent Hard Cardiovascular Outcomes Associated With Socioeconomic Status
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Socioeconomic Status
- Sponsor
- Karolinska Institutet
- Enrollment
- 30191
- Primary Endpoint
- first recurrent atherosclerotic cardiovascular disease event (rASCVD)
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
This is a nationwide cohort study on real-world patients (n≈30,000) surviving a first myocardial infarction (MI) 2006-2013 and alive to attend a routine 1-year follow-up. Associations between Socioeconomic Status (SES) and secondary preventive actions (SPAs) throughout the first year is studied and assessed as possible mechanisms underlying the increased risk of a first recurrent hard cardiocvascular (CV) outcome, recurrent atherosclerotic cardiovascular disease (rASCVD), in patients with low Socioeconomic Status during long-term follow-up (2006-2018).
Investigators
Per Svensson
Associate professor
Karolinska Institutet
Eligibility Criteria
Inclusion Criteria
- •Swedish resident
- •Alive and registered in The Swedish Websystem for Enhancement and Development of Evidence based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART)'s secondary prevention subregistry between 1 January 2006 and 31 December 2013 at the 1-year-revisit
Exclusion Criteria
- •Age \>76 years at baseline
- •Missing data for disposable household income
- •History of MI, stroke, coronary artery bypass graft (CABG), or percutaneous coronary intervention (PCI) prior to the index MI
- •Not present in initial care registry (RiksHIA)
- •Date of index MI before 2004 or missing
- •revisit outside 13±2 month window post-MI
Outcomes
Primary Outcomes
first recurrent atherosclerotic cardiovascular disease event (rASCVD)
Time Frame: from date of 1-year visit post-MI (baseline) until date of outcome, censoring or study end (2018)
composite outcome including non-fatal MI (I210-I214, I219, I220, I221, I228 or I229) or coronary heart disease death (CHD) (I210-I214, I219, I220, I221, I228, I229, I461 or I469) or fatal or non-fatal ischemic stroke (I630-I635, I638 or I639) according to the International Classification of Diseases 10th edition (ICD-10)