Notify 2: An Evaluation of the Impact of Notification of Incidental Coronary Artery Calcium on Statin Rates
试验速览
- 阶段
- 不适用
- 入组人数
- 600
- 试验地点
- 1
- 主要终点
- Statin prescription rate
研究概览
简要总结
The primary objective is to estimate the impact of notification of primary care provider and patient of at least moderate incidental coronary artery calcification (CAC) on a prior non-gated chest CT on statin prescription rates at 4 months among patients without a clinical history of atherosclerotic cardiovascular disease not actively on statin therapy. This study will determine if notifying patients and their primary care clinician about an existing finding will influence shared decision-making around statins between patients and their primary care clinician.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age greater than or equal to 18 and less than 85
- •Non-gated chest CT from 1/1/2016-6/30/2020 with algorithm screening estimating CAC score of at least 100 Agatston Units with radiologist confirmation of moderate or severe CAC
- •Encounter with Palo Alto VA affiliated primary care since 2020
排除标准
- •Prior diagnosis of coronary artery disease, peripheral artery disease, or cerebrovascular disease
- •Metastatic cancer or active cancer undergoing chemotherapy
- •CT coronary angiogram since 2016
- •Invasive Coronary angiogram since 2016
- •CAC scan since 2016
- •Statin therapy within prior 6 months
- •Prior ezetimibe or PCSK9 inhibitor therapy
- •Prior rhabdomyolysis with statin therapy
- •Schizophrenia
- •Substance abuse disorder (alcohol, amphetamines, cocaine, opioids)
研究组 & 干预措施
Notification
Notification of the presence of at least moderate coronary artery calcium on a prior non-gated chest CT
干预措施: Notification (Other)
Usual Care
结局指标
主要结局
Statin prescription rate
时间窗: 4 months
Prescription of statin medication
次要结局
未报告次要终点
研究者
Alexander Sandhu
Instructor of Medicine
Stanford University