Consequences of Hypoglycemia on Intensive Care Unit (ICU) Patients

Completed

• Conditions: Critical Illness

• Registration Number: NCT00662922
• Lead Sponsor: University Hospital Muenster

Brief Summary

Hypoglycemia occurs frequently during intensive blood glucose control in critically ill patients. The incidence of hypoglycaemia is associated with impaired outcome. However, it is hitherto unknown if hypoglycaemia itself predisposes patients to neurological impairment, e.g. cognitive dysfunction, or if it is the underlying medical condition that makes the patient prone to a high risk of hypoglycaemia and, concomitantly, neurocognitive impairment. Therefore we investigate neurocognitive function in patients who had hypoglycemias during their intensive care stay and compare the results to patients without hypoglycaemia whose medical conditions are matched to the hypoglycaemia patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-04
• Study First Submitted: 2008-04-16
• Study First Submitted QC: 2008-04-17
• Study First Posted: 2008-04-21
• Primary Completion: 2008-09
• Study Completion: 2008-09
• Status Verified: 2010-01
• Last Update Submitted: 2010-01-08
• Last Update Posted: 2010-01-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 74

Inclusion Criteria

• all patients

Exclusion Criteria

• clinical diagnosis of diabetes mellitus
• brain injury of any kind prior to or upon ICU-admission
• pre-existing mental or psychiatric disorder
• terminal kidney or liver failure prior admission
• drug abuse,
• CPR > 5 min
• HIV
• Lues

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
neurocognitive function	1 year after ICU discharge

Secondary Outcome Measures

Name	Time	Method
neurocognitive function	2,3, and 4 years after ICU discharge

Trial Locations

Locations (1)

Department of Anesthesiology and Intensive Care, University Hospital Münster; 🇩🇪 Münster, Germany