Investigating the role of the vagus nerve on risk-taking behavior

Completed

• Conditions: Risk-taking behavior of healthy participants; Decision-making; Rist-taking behavior

• Registration Number: NL-OMON51578
• Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2024-04-08
• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Healthy right handed participants with ages between 18 and 35 years old

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded
from participation in this study:
• Age above 35 years.
• Facial or ear pain.
• Metal implants including pacemakers.
• Pregnancy.
• Personal or family history of seizure, mood, or cardiovascular disorders.
• Dependence on alcohol.
• Recent illicit drug use, on any pharmacological agents known to increase
seizure risk.

Considering our hypothesis that the nVNS will send a similar signal to the CNS
that the one generated by the prolonged use of probiotics, we will exclude
participants that currently include probiotics in their diet as a measure to
avoid confounding factors.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is the change in risk-taking behavior, measured using<br /><br>the MGT and comparing the participant*s choices during active nVNS and sham<br /><br>nVNS (Dantas et al., 2021). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Besides the calculation of participants* risk-taking behavior, their average<br /><br>choices of values and probabilities are also estimated. Finally, we also<br /><br>analyze participants* response times. </p><br>