TROG 14.04 HART: Deep Inhalation Breath Hold for reduction of cardiac toxicity in patients with left-sided breast cancer undergoing radiotherapy, HART (Heart Avoiding Radiation Therapy)
- Conditions
- breast cancerCancer - Breast
- Registration Number
- ACTRN12617000237381
- Lead Sponsor
- Trans Tasman Radiation Oncology Group
- Brief Summary
The HART trial tested the feasibility of Deep Inhalation Breath Hold (DIBH) to reduce heart radiation dose in left sided breast cancer patients in a multicentre setting. Patient reported outcomes such as anxiety associated with holding their breath were also investigated in comparison to right-sided breast cancer patients treated in free breathing (normal breathing). The trial confirmed that DIBH has the potential to reduce the radiation dose to the heart for left sided breast cancer patients receiving radiotherapy in a variety of settings. There was a slightly higher anxiety scores among DIBH patients suggest the act of breath holding, or knowledge of the purpose of DIBH, may increase patient anxiety. However, this increased anxiety reduced to levels similar to the control group of right sided breast cancer patients throughout the course of their treatment.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 62
Females greater than or equal to 18 years
Written informed consent
Breast cancer with an indication for radiotherapy after breast conserving surgery or mastectomy
Significant respiratory illnesses or breathing difficulties who are unable to comply with DIBH
Bilateral breast cancer
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method