The Effect of Blood Transfusion on Venoarterial PCO2 Difference in Cardiac Surgery

Completed

• Conditions: Cardiac Procedure Complication

• Registration Number: NCT03245502
• Lead Sponsor: Turkiye Yuksek Ihtisas Education and Research Hospital

Brief Summary

Venoarterial CO2 difference(delta PCO2), lactate, central venous oxygen saturation(ScVO2) will be recorded in several steps in coronary artery bypass graft and valvular cardiac operations. The patients will be divided into two groups as Transfused, and Non-Transfused Groups observationally. The trend of delta CO2, lactate, ScVO2, postoperative creatinine values, postoperative complications and 28 days mortality will be compared.

Detailed Description

Preoperative creatinine values, demographic data, comorbidities will be recorded in ASA I-II elective coronary artery and valvular cardiac surgery patients. Intraoperative delta PCO2, lactate, ScVO2 will be recorded in several steps. The patients will be divided into two groups as Transfused, and Non-Transfused Groups observationally. The trend of delta CO2, lactate, ScVO2, postoperative creatinine values, postoperative complications and 28 days mortality will be compared.

Study Timeline

• Study First Submitted: 2017-08-08
• Study First Submitted QC: 2017-08-09
• Study First Posted: 2017-08-10
• Study Start: 2017-08-20
• Primary Completion: 2017-11-01
• Status Verified: 2017-12
• Study Completion: 2017-12-01
• Last Update Submitted: 2017-12-14
• Last Update Posted: 2017-12-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 127

Inclusion Criteria

• Elective cardiac surgery, stable cardiac function

Exclusion Criteria

• Clinical signs of heart failure, symptomatic cerebral or peripheral failure, uncontrolled diabetes mellitus

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Complication	5 days	The postoperative neurologic, renal, hepatic, respiratory complications

Secondary Outcome Measures

Name	Time	Method
Mortality	28 days	mortality

Trial Locations

Locations (1)

Turkiye Yuksek Ihtisas Education and Research Hospital; 🇹🇷 Ankara, Turkey