Respiratory Weaning Following Cardiac Surgery.

Withdrawn

• Conditions: Respiratory Insufficiency
• Interventions: Other: Combined Thoracic Echography Record

• Registration Number: NCT02821429
• Lead Sponsor: University Hospital, Toulouse

Brief Summary

Respiratory weaning failure worsens prognostic of patients following on-pump cardiac surgery. There are increasing evidences that pulmonary, diaphragmatic or cardiologic echographies are useful in order to improve this critical medical status.

Based both on a previous study conducted in the critical care unit of Purpan and on literature we hypothesize that a combined thoracic echography score could be of interest. We make the hypothesis that the use of a score based on thoracic combined echography (ETC = cardiac, pulmonary and diaphragmatic) allows to predict the failure of respiratory weaning in cardiac surgery and allows to improve the characterization of the causes of this failure

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2016-06-28
• Study First Submitted QC: 2016-06-28
• Study First Posted: 2016-07-01
• Primary Completion: 2019-01
• Study Completion: 2019-01
• Status Verified: 2019-06
• Last Update Submitted: 2019-06-05
• Last Update Posted: 2019-06-06

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Adult (> 18 years old) beneficiating of mechanical ventilation following cardiac surgery
• Weaning test period
• Patient insured under the French social security system

Exclusion Criteria

• Tracheostomy
• Neurological disorders
• Need for prophylactic non invasive ventilation.
• Global obstructive lung disease with a forced expiratory volume < 50%.
• Judicial protection
• Patient already included in a trial still running.
• Pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patient with mechanical ventilation	Combined Thoracic Echography Record	Patient will be followed with combined Thoracic Echography Record

Primary Outcome Measures

Name	Time	Method
Evaluation of predictive value of combined Thoracic Echography (ETC) as assessed by difference in the ETC score before and after extubation	1 hour after the weaning test and 48h after

Secondary Outcome Measures

Name	Time	Method
Evaluation of predictive value of combined Thoracic Echography (ETC) as assessed T tube Test score difference between patient who succeed or failed the weaning test	H0 and 48h after the weaning test
Evaluation of diagnostic value of combined Thoracic Echography (ETC) after failure to weaning test as assessed be ECT scores collected	H0, H1 and H48

Trial Locations

Locations (1)

University Hospital Toulouse; 🇫🇷 Toulouse, France