sage behavior and nicotine kinetics during ad libitum use of tobacco heating systems, e-cigarettes, and tobacco cigarettes - Nicotide 2

MU Klinikum München - Klinik für Psychiatrie und Psychotherapie0 个研究点目标入组 45 人开始时间: 2022年1月4日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Other general inclusion criteria:
•- 12-hour abstinence.
•- CO < 5ppm; measurement in expiratory air using micro-smokerlyzer (Bedfont Scientific Ltd).
•- Nicotine plasma concentration at baseline < 10 ng/ml.
•- Capacity to agree to an informed consent.
•Special inclusion criteria for electric cigarette users:
•- experienced user of e-cigarettes with pod system (JUUL, myblu) for >3 months, daily use
•- No daily use of conventional tobacco cigarettes for >3 months.
•Special inclusion criteria for IQOS users:
•- experienced IQOS user for > 3 months, daily consumption of at least 10 heets of tobacco sticks
•- no daily use of conventional tobacco cigarettes for > 3 months
•Special inclusion criteria for smokers:
•- smoker for > 5 years
•- consumption of > 10 cigarettes/day

•Exclusion criteria
•- patients under 18 years of age or over 55 years of age
•- acute psychiatric illness according to ICD-10/DSM IV
•- other severe psychiatric illnesses
•- acute suicidal tendencies
•- existing pregnancy
•- drug, medication or alcohol abuse at the time of the study
•- current malignant cancer during the last 5 years
•- severe internal diseases, especially cardiovascular diseases, such as
•manifest arterial hypertension, severe heart disease (DCM, history of myocardial infarction), cardiac pacemaker
•- respiratory diseases (e.g. asthma, COPD)
•- severe active infectious diseases
•- CO >5 ppm in expirium
•- Nicotine plasma concentration at baseline >10 ng/ml
•- no capacity to agree to an informed consent
•- Other circumstances that, in the opinion of the responsible study physician, militate against the patient's participation in this study.

发起方

MU Klinikum München - Klinik für Psychiatrie und Psychotherapie