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Study About Effectiveness of Silver-Containing Textiles for Treatment of Acute Neurodermatitis

Phase 3
Completed
Conditions
Neurodermatitis
Registration Number
NCT00196430
Lead Sponsor
University Medicine Greifswald
Brief Summary

The purpose of this study is to investigate whether the treatment of acute neurodermitis with silver-contained textiles is equivalent or more effective to the conservative exogenous treatment with a corticosteroid. Secondary aim is to define skin comfortability of the textiles.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
32
Inclusion Criteria
  • Clinical diagnosis of acute Neurodermitis
  • Age: 2-70 years
  • Patients are mobile
  • Patient's information and willingness to participate
Exclusion Criteria
  • Acute viral infection (herpes zoster, eczema herpeticum)
  • Acute staphylodermas
  • Other skin-diseases affecting outcomes of intervention (e.g. psoriasis)
  • Current UV-Treatment
  • Current other immunosuppressive or immunomodulated Therapy
  • Current antimicrobial Therapy (e.g. antibiotics)
  • Severe general diseases (e.g. melanoma, renal insufficiency, autoimmune diseases)
  • Pregnancy
  • Fertile females without effective contraception

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
SCORAD at days -3,0,7,14,28,56 for every group
Secondary Outcome Measures
NameTimeMethod
Influence of silver containing textiles in reducing bacterial skin colonization (especially Staph. aureus)
Consumption of corticosteroids at days 0-28
Consumption of corticosteroids at days 28-56
Pruritus under textiles
Evaluation of quality of life

Trial Locations

Locations (1)

Clinic and Polyclinic of Dermatology, Ernst-Moritz-Arndt-University of Greifswald

🇩🇪

Greifswald, Fleischmannstr. 42-44, Germany

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