Comparison of Three Calcium Supplements With Regard to Their Metabolic Effects in Healthy Adults
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 31
- Primary Endpoint
- Lipids in blood
Study Overview
Brief Summary
The study was conducted to investigate the metabolic effects of three different calcium compounds in healthy adults.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •age 18 - 40 years
Exclusion Criteria
- •diseases of the gastrointestinal tract
- •pregnancy
- •the intake of any medication (e. g. for thyroid gland)
- •intake of dietary supplements
Outcomes
Primary Outcomes
Lipids in blood
Time Frame: after 4 weeks of each intervention
Lipids and lipoprotein concentration in serum.
Serum mineral concentration
Time Frame: after 4 weeks of each intervention
Calcium and Phosphate (and others) concentration in serum.
Stool mineral concentration
Time Frame: after 4 weeks of each intervention
Calcium and Phosphate concentration (and others) in stool from a three day stool collection
Sterols
Time Frame: after 4 weeks of each intervention
Neutrals sterols and bile acids in stool from a three day stool collection
Dietary intake
Time Frame: after 4 weeks of each intervention
Evaluation of the dietary intake using a three day weighed dietary record.
Urine mineral concentration
Time Frame: after 4 weeks of each intervention
Calcium and Phosphate concentration (and others) in urine from a three day urine collection
Secondary Outcomes
No secondary outcomes reported
Investigators
Gerhard Jahreis
Prof. Dr. Gerhard Jahreis
University of Jena