Study about deficiency of thyroid hormones following removal of larynx in laryngeal cancers

Completed

Conditions: Medical and Surgical,

Registration Number: CTRI/2018/12/016652

Lead Sponsor: DR Architha Menon P

Brief Summary: The study is to determine the incidence of hypothyroidism orhypoparathyroidism in patients diagnosed with laryngeal and hypopharyngealmalignancies undergoing totallaryngectomy or laryngopharyngectomy with hemithyroidectomy with or without post operative radiation therapy .

Helps to assess subclinical and clinicalhypothyroidism and hypoparathyroidism and treatment can be commenced as earlyas possible. Hence improves the lifestyle and general well being of the patient.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 20

Inclusion Criteria

Patients with primary cancer of larynx and hypopharynx undergoing total laryngectomy/laryngopharyngectomy with hemithyroidectomy Patients undergoing radiotherapy post laryngectomy.

Exclusion Criteria

Patients with preoperative thyroid disease.
Patients with second primary or those who received radiotherapy prior to surgery for any cause.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the incidence of hypothyroidism and hypoparthyroidism	Before surgery \| 1 week post surgery \| 6weeks post surgery \| 4weeks post radiation

Secondary Outcome Measures

Name	Time	Method
Helps to assess subclinical and clinical hypothyroidism and hypoparathyroidism and treatment can be commenced as early as possible. Hence improves the lifestyle and general well being of the patient	Before surgery

Trial Locations

Locations (1): Kasturba Medical college Manipal
🇮🇳
Udupi, KARNATAKA, India
Kasturba Medical college Manipal
🇮🇳Udupi, KARNATAKA, India
DR ARCHITHA MENON P
Principal investigator
9538417393
archz5691@gmail.com