The outcomes of hypo fractionated radiotherapy in breast cancer patients
Phase 3
- Conditions
- Breast Cancer.malignant neoplasm of breastC50-C50
- Registration Number
- IRCT2014102519675N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
patients with early stage breast cancer (T1-T2 N0) below 70 years old who have undergone breast conserving surgery and fill in the informed consent.
Exclusion criteria: history of collagen vascular disease; field separation more than 22Cm; ejection fraction less than 50%; lost in follow up.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Skin toxicity. Timepoint: Every week during intervention then every two weeks in the first month after intervention and then every 3 months up to 2 years. Method of measurement: Based on NCCI Common Toxicity Criteria (CTC) version 20.;Cardiac toxicity. Timepoint: Before intervension and 4 months after intervention. Method of measurement: Echocardiography.;Lung toxicity. Timepoint: Before intervention , 6 and 12 months after intervention. Method of measurement: Spirometry.
- Secondary Outcome Measures
Name Time Method Cosmetic outcome. Timepoint: 2 years after intervention. Method of measurement: Based on Harvard Criteria.