NL-OMON38165已完成不适用
HYpertension and Preeclampsia Intervention Trial in the Almost Term Patient (HYPITAT-2) - HYPITAT-2
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 680
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Patients 18 years of age or older which have gestational hypertension or pre-eclampsia at a gestational age between 34+0 and 37+0 weeks of gestation. A diagnosis of pregnancy induced hypertension is made in case the diastolic blood pressure is above 100 mmHg at two occasions at least six hours apart in a woman who was normotensive until at least 20 weeks of gestation. A diagnosis of preeclampsia is made in case the diastolic blood pressure is above 90 mmHg and there exists a proteinuria > 300 mg total protein in a 24 hour urine collection.
- •inclusion criteria:
- •- Maternal age * 18 years
- •- Gestational hypertension defined as:
- •o 100 mmHg < diastolic blood pressure < 110 mmHg
- •o at two occasions at least six hours apart
- •- Pre-eclampsia defined as:
- •o 90 mmHg * diastolic blood pressure < 110 mmHg
- •o at two occasions at least six hours apart
- •o 0,3 g * proteinuria < 10 g
- •o proteinuria > 300 mg total protein in an 24 hour urine collection
- •- Gestational age between 34+0 and 37+0 weeks
- •- Informed consent
- •- Women with singleton or multiple pregnancy
- •- Women with a child in cephalic or breech presentation
排除标准
- •* Diastolic blood pressure * 110 mmHg despite medication
- •* Systolic blood pressure * 170 mmHg despite medication
- •* Renal disease
- •* Heart disease
- •* Seropositive for HIV
- •* HELLP syndrome
- •* Pulmonary edema or cyanosis
- •* Proteinuria * 5 g/L
- •* Oliguria < 500 mL in 24 hours
- •* Non-reassuring foetal heart rate
- •* Foetal abnormalities including abnormal karyotype.
- •* Severe preeclamptic complaints, such as frontal headache
- •* Ruptured membranes
研究者
相似试验
已完成
不适用
HYPITAT-IIPreeclampsia, gestational hypertension, induction of labourPreeclampsie, zwangerschaps hypertensie, inleiden van de baringNL-OMON29619Dutch consortium for studies in obstetrics, gynaecology, fertility, neonatology, gynaecological oncology, and urogynaecology.680
尚未招募
不适用
Hypitat.Hypertensie in de zwangerschapNL-OMON28724ZonMw250
Unknown
4 期
Anti-Hypertensive Treatment In Stable Pregnant Women With Severe Pre-Eclampsia (Metildopape)PreeclampsiaNCT01361425Professor Fernando Figueira Integral Medicine Institute200
尚未招募
不适用
The CHIPS Trial (Control of Hypertension In Pregnancy Study)chronic hypertensiongestational hypertension1002690810057166NL-OMON35551THE UNIVERSITY OF BRITISH COLUMBIA, Departments of Obstetrics and Gynaecology & Medicine220
Unknown
不适用
China Obstetrics Alliance Cohort StudyPreeclampsiaNCT03038555The Third Affiliated Hospital of Guangzhou Medical University900