Effectiveness of Prophylactic Bolus Ephedrine Versus Norepinephrine for Management of Post Spinal Hypotension
Completed
- Conditions
- Comparing Ephedrine With Norepinephrine for Mangement Postspinal Hypotension
- Registration Number
- NCT05522088
- Lead Sponsor
- Wachemo University
- Brief Summary
This study was conducted to compare the effectiveness of ephedrine versus norepinephrine for management of hypotension after spinal anesthesia for mothers undergoing elective cesarean section
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 84
Inclusion Criteria
- ASA class II and ages ranging from 18-35 years were included in the study
Exclusion Criteria
- pregnant women with preeclampsia/eclampsia, baseline hypertension (SBP> 140 mm Hg), BMI> 30 kg/m2, failed spinal, spinal anaesthesia converted to general anaesthesia, contraindication for spinal anaesthesia and mother with cardiovascular, renal or hepatic disease.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to compare mean blood pressure (MAP) between the groups From March,01 to April, 30/2022
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms of ephedrine and norepinephrine in managing postspinal hypotension during cesarean sections?
How does the effectiveness of prophylactic bolus ephedrine compare to norepinephrine in resource-limited settings for postspinal hypotension?
Are there specific biomarkers that predict maternal response to ephedrine or norepinephrine in postspinal hypotension management?
What are the potential adverse events associated with ephedrine and norepinephrine use in postspinal hypotension during elective cesarean sections?
What alternative vasoactive agents or combination therapies are being explored for postspinal hypotension in obstetric anesthesia?
Trial Locations
- Locations (1)
Wachemo University
🇪🇹Hosa'ina, Ethiopia
Wachemo University🇪🇹Hosa'ina, Ethiopia