Comparison Of Dexmedetomidine And Dexamethasone As An Adjuvant To Ropivacaine 0.5 Percentage In Ultrasound Guided Supraclavicular Brachial Plexus Block In Patients Undergoing Upper Limb Surgeries: A Randomised Clinical Trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Onset and duration of sensory and motor block (using HOLLMEN SCALE) using 0.5% Ropivacaine and dexmedetomidine as adjuvant
研究概览
简要总结
Regional anesthesia techniques have advantages including excellent pain control, reduced side- effects, and shortened stay in the post anesthesia care unit. Ultrasound-guided regional blocks are considered safer with better success rates. Supraclavicular block has high efficacy for providing anaesthesia in upper limb surgeries. Ropivacaine with lesser cardiac side effects is the preferred local anaesthetic agent. Dexmedetomidine and Dexamethasone is used to reduce the onset time, prolong the analgesic, and motor blockade effect without the systemic side effects and reduce total dose of local anesthetic requirement. Here, in our study we determine the duration of analgesia and compare the hemodynamic parameters with two different drugs of Dexmedetomidine and Dexamethasone with 0.5% Ropivacaine. We also try to find any adverse reaction to the study drugs. A total of 52 patients undergoing upper limb surgeries will be divided into two groups: Group A and Group B by block randomization. Group D will receive 20 ml of 0.5% Ropivacaine with 2 ml of 20 mcg Dexmedetomidine and Group X will receive 20 ml of 0.5% Ropivacaine with 2 ml of 8mg Dexamethasone. Duration of analgesia, onset of sensory and motor block, time requirement of rescue analgesia will be studied. Hemodynamic parameters and adverse effects will be recorded. The findings and observations made during the entire study will be tabulated, graphically depicted whenever possible, statistically analyzed and inference will be drawn.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients of age group 18 to 60 years.
- •Patients of American Society of Anaesthesiologists (ASA) physical status grade I or II.
排除标准
- •Patients with hypertension, diabetes mellitus, autonomic neuropathy, peripheral nerve injury
- •Pregnancy or lactation.
- •Patients on anticoagulants or bleeding disorders.
- •Uncooperative/unwilling patients.
- •Local site infection.
结局指标
主要结局
Onset and duration of sensory and motor block (using HOLLMEN SCALE) using 0.5% Ropivacaine and dexmedetomidine as adjuvant
时间窗: Baseline and time when patient complains of pain and can start moving his limbs
次要结局
- Onset & duration of sensory & motor block (using HOLLMEN SCALE) using 0.5% ropivacaine & dexamethasone as adjuvant(Baseline & time taken for patient to feel pain & move limbs)
研究者
Arivumadhi Sankar
Regional Institute of Medical Sciences
