Effect of intra peritoneal instillation of Magnesium sulfate on Post operative Analgesia in laparoscopic cholecystectomy. A Prospective Cohort study.

Not yet recruiting

• Conditions: Administration,

• Registration Number: CTRI/2021/01/030578
• Lead Sponsor: DrJijo Jose Government Medical CollegeKozhikode

Brief Summary

It’s a study of post operative Analgesia in laparoscopic cholecystectomy following intra peritoneal instillation of Magnesium sulfate .MgSO4 30mg/kg diluted in 30ml normal saline which is instilled through the port by the surgeon after the resection of gall bladder and patient kept trendenlenberg position of about 10 degree after the drug administration and observed for 24 hours post operative period for duration of analgesia and analgesic requirements .

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-01-18
• Study Start: 2021-01-25

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1)Patients with American society of Anaesthesiologist class 1 or 2 undergoing elective cholecystectomy 2)BMI between 18 and 30.

Exclusion Criteria

1)Patients refusal 2)Pregnant and breast feeding 3)Patient on beta blocker 4)Patient with autonomic dysfunction 5)Patients with chronic pain on opioids and other analgesics 6)History of allergy to study drug.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of analgesia,Mean pain scores during 1st 24 hours of post-operative period,Number of total doses of analgesics requirement at 24 hour and incidence of shoulder pain	Duration of analgesia,Mean pain scores during 1st 24 hours of post-operative period,Number of total doses of analgesics requirement at 24 hour and incidence of shoulder pain

Secondary Outcome Measures

Name	Time	Method
Recovery profile,Post instillation hero dynamic changes in terms of heart rate ,systolic blood pressure,diastolic blood pressure,sedation,Post operative nausea and vomiting and respiratory depression if any	Observed for first 24 hour of post operative period

Trial Locations

Locations (1)

Medical College Hospital Kozhikode ,Department of Anesthesiology.; 🇮🇳 Kozhikode, KERALA, India

Medical College Hospital Kozhikode ,Department of Anesthesiology.

🇮🇳Kozhikode, KERALA, India

DrJijo Jose Medical College HospitalGovernment Medical College Kozhikode

Principal investigator

9495591964

jjose6391@gmail.com