POST OPERATIVE ANALGESIA IN LAPAROSCOPIC CHOLECYSTECTOMY FOLLOWING INTRA PERITONEAL MAGNESIUM SULFATE-AN OBSERVATIONAL STUDY
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Duration of analgesia,Mean pain scores during 1st 24 hours of post-operative period,Number of total doses of analgesics requirement at 24 hour and incidence of shoulder pain
研究概览
简要总结
It’s a study of post operative Analgesia in laparoscopic cholecystectomy following intra peritoneal instillation of Magnesium sulfate .MgSO4 30mg/kg diluted in 30ml normal saline which is instilled through the port by the surgeon after the resection of gall bladder and patient kept trendenlenberg position of about 10 degree after the drug administration and observed for 24 hours post operative period for duration of analgesia and analgesic requirements .
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with American society of Anaesthesiologist class 1 or 2 undergoing elective cholecystectomy 2)BMI between 18 and 30.
排除标准
- •Patients refusal 2)Pregnant and breast feeding 3)Patient on beta blocker 4)Patient with autonomic dysfunction 5)Patients with chronic pain on opioids and other analgesics 6)History of allergy to study drug.
结局指标
主要结局
Duration of analgesia,Mean pain scores during 1st 24 hours of post-operative period,Number of total doses of analgesics requirement at 24 hour and incidence of shoulder pain
时间窗: Duration of analgesia,Mean pain scores during 1st 24 hours of post-operative period,Number of total doses of analgesics requirement at 24 hour and incidence of shoulder pain
次要结局
- Recovery profile,Post instillation hero dynamic changes in terms of heart rate ,systolic blood pressure,diastolic blood pressure,sedation,Post operative nausea and vomiting and respiratory depression if any(Observed for first 24 hour of post operative period)