Assessment of the Effectiveness of Local Ablathermy Radio Frequency (RF) Bronchial Tumors Primitive Stage IA Non-surgical Patients. Phase II Multicenter National
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Malignant Non-small Cell Neoplasm of Lung Stage Ia
- Sponsor
- Institut Bergonié
- Enrollment
- 42
- Locations
- 9
- Primary Endpoint
- Local Tumor Control Rate 1 Year After Percutaneous Radiofrequency Ablation (RFA)
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Lung tumors of non-small cell stage 1A are usually treated surgically but many patients are not operable because of their condition or respiratory problems associated with it. The treatment is then suggested that local radiotherapy is conventionally carried out in split mode for 6 weeks at a dose of 60-65 Gy irradiation mode This exposes the patient to complications, including post-radiation pneumonitis.
Detailed Description
Lung tumors of non-small cell stage 1A are usually treated surgically but many patients are not operable because of their condition or respiratory problems associated with it. The treatment is then suggested that local radiotherapy is conventionally carried out in split mode for 6 weeks at a dose of 60-65 Gy irradiation mode This exposes the patient to complications, including post-radiation pneumonitis. This can be problematic in patients with respiratory failure for which surgical treatment has been challenged. Radiofrequency pulmonary developed as a therapeutic alternative, it has the advantage of being performed in a session with less toxicity in the lung parenchyma
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Local Tumor Control Rate 1 Year After Percutaneous Radiofrequency Ablation (RFA)
Time Frame: one year after percutaneous radiofrequency ablation (RFA)
local control is defined as the absence of progression of the ablated site. rate is defined as the number of alive patient without local progression divided by the number of patients alive at one year.
Secondary Outcomes
- 3-year Overall Survival (OS) Rate(3 years after RFA)
- Local Tumor Control Rate 3 Years After Percutaneous Radiofrequency Ablation (RFA)(three years after percutaneous radiofrequency ablation (RFA))
- 1-year Overall Survival (OS) Rate(1 year after RFA)