A Comparative Clinical Study of Raasna Guggulu and Raktamokshana along with Raasna Guggulu in Gridhrasi (Sciatica)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Outcome will be measured with the parameters -
研究概览
简要总结
Gridhrasi is described as oneof Vatavyadhi and included under 80 types of Nanatmaja Vatavyadhidescribed by Acharya Charaka. It is characterized by the onset of Ruka(pain), Toda (pricking pain), Stambha (stiffness), Spandana (pulsation)initially in Sphika (buttock) and then radiating distally to posterioraspect of Kati (waist), Pristha (back), Uru (thigh), Janu(knee), Jangha (calf) up to Pada (foot). On the basis of symptoms of Gridhrasi, itcan be equated with Sciatica in modern science.Manyformulations and procedures have been given by Acharyas in the treatmentof Gridhrasi (Sciatica) among them Raasnaguggulu and Raktamokshana has been selected for the study. As in Gridhrasi(Sciatica) mainly Vata dosha isvitiated,Raasna and Guggulu are among best drugs for vitiated Vata dosha by Acharya Charaka and Acharya Vagbhatta respectively*.*Thus, Raasna guggulu can be a good therapeutic option. Moreover, as Snayuand Rakta dhatu are involved in Gridhrasi (Sciatica), so Raktamokshanacan also be an efficient therapeutic option in this disease. Among variousmethods of Raktamokshana, Shringa Yantra is one of the potentinstruments described by AcharyaSushruta for the pacificationof vitiated Vata dosha.
AIM
Tocompare the effect of Raasnaguggulu (orally)alone and Raktamokshana by modified Shringa Yantra along with Raasna guggulu (orally) in the management of Gridhrasi(Sciatica).
OBJECTIVES
1. To evaluate the effect of Raktamokshanaby modified Shringa Yantra along with Raasna guggulu in managementof Gridhrasi (Sciatica).
2. To evaluate the clinicalefficacy of Raasna guggulualonein management of Gridhrasi (Sciatica).
3. To provide a cost effective and safetreatment for the patients of Gridhrasi (Sciatica).
4. To explore the literature regarding Raktamokshanaand Gridhrasi (Sciatica)inAyurvedic and modern text.
研究设计
- 研究类型
- Interventional
- 分配方式
- Adaptive randomization, such as minimization
- 盲法
- Open Label
入排标准
- 年龄范围
- 16.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient who have classical sign and symptoms of Gridhrasi Willingness of patients for study.
排除标准
- •Pandu (Anaemic, Hb < 10 gm%) Garbhini (Pregnancy) Shosha (Tuberculosis) Diabetes Mellitus Uncontrolled Hypertension Malignancy of spine or other organs History with spine fracture (trauma) Cardiac diseases HIV positive Hepatitis A,B,C positive.
结局指标
主要结局
Outcome will be measured with the parameters -
时间窗: Total 3 sittings of Raktamokshana on 14 days interval for 28 days | 2gm of Raasna Guggulu (2 tablets of 500mg each twice a day) for 28 days
1. Ruka (Pain/Discomfort) in lower back and lower limbs
时间窗: Total 3 sittings of Raktamokshana on 14 days interval for 28 days | 2gm of Raasna Guggulu (2 tablets of 500mg each twice a day) for 28 days
2. Stambha (Stiffness) in lower back and lower limbs
时间窗: Total 3 sittings of Raktamokshana on 14 days interval for 28 days | 2gm of Raasna Guggulu (2 tablets of 500mg each twice a day) for 28 days
3. Aruchi (dislike / aversion of food)
时间窗: Total 3 sittings of Raktamokshana on 14 days interval for 28 days | 2gm of Raasna Guggulu (2 tablets of 500mg each twice a day) for 28 days
4. Spandana (Throbbing / Pulsating) in lower back and lower limbs
时间窗: Total 3 sittings of Raktamokshana on 14 days interval for 28 days | 2gm of Raasna Guggulu (2 tablets of 500mg each twice a day) for 28 days
5. Gaurava (Heaviness / Lassitude)in lower back and lower limbs
时间窗: Total 3 sittings of Raktamokshana on 14 days interval for 28 days | 2gm of Raasna Guggulu (2 tablets of 500mg each twice a day) for 28 days
次要结局
- Reduction in angle of SLR test(Total 3 sittings of Raktamokshana on 14 days interval for 28 days)