Effectiveness of Patient-Controlled Intravenous Analgesia (PCIA) With Fentanyl Background Infusion for Total Hip Replacement
Trial Snapshot
- Phase
- Phase 1
- Status
- Completed
- Sponsor
- Egymedicalpedia
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Fentanyl Background
Study Overview
Brief Summary
To enhance post-operative pain management, patient-controlled intravenous analgesia (PCIA) has been employed. The fentanyl background PCIA therapy was created to solve the limitations of IV-based PCIA, such as programming errors, mobility limitations, and the risk of needle stick injuries. The goal of this trial was to observe how fentanyl patient-controlled intravenous analgesia pump (PCIA) and background infusion is worked in patients with post-total hip replacement analgesia.
Detailed Description
Significant efforts to enhance the treatment of postoperative pain have resulted in the formulation and implementation of pain management guidelines, as well as the introduction of acute pain services in several hospitals during the last two decades.
Recent research, however, suggests that postoperative pain is still poorly controlled .
Hip replacement procedures are prevalent among the elderly, and they are significantly more painful .
The patient may suffer greatly as a result of the pain, which can also affect physiological functioning caused by hormonal changes caused by sympathetic nervous system activation .
Anaesthesiologists and patients alike are concerned about pain management following major surgery. It should also be mentioned that every pain management medication has certain side effects, especially when an opioid is utilized .
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- — to 40 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients with total fracture of Hip bones
Exclusion Criteria
- •History of mental or neurological complaints,
- •Opioid and local anaesthetic allergies,
- •Opioid tolerance,
- •Smoking history,
- •local infection,
- •cemented total hip arthroplasty (THA), revision THA,
- •preoperative DVT,
- •renal failure,
- •bleeding tendency due to anticoagulant therapy
Arms & Interventions
fentanyl infusion Group
According to the body weight, 2 ug/kg fentanyl was diluted to 100 ml with normal saline. with rate of 2 mL/h infusions, 10 min lockout time and Initial PCIA analgesia regimen consisting of a 0.5 mL bolus was commenced to be given to the patients postoperative with evaluation the pain
Intervention: Fentanyl (Drug)
NO fentanyl infusion Group
All patients underwent combined spinal and epidural anesthesia (CSEA) with 2 ml of 0.5 % hyperbaric bupivacaine only
Intervention: Fentanyl (Drug)
Outcomes
Primary Outcomes
Fentanyl Background
Time Frame: from 0 hours to 36 hours after the completion of the operation
Effectiveness of Patient-Controlled Intravenous Analgesia (PCIA) With Fentanyl Background Infusion for Total Hip Replacement
Secondary Outcomes
No secondary outcomes reported