JPRN-UMIN000012342尚未招募未知
the effect of febuxostat on vascular endothelial function in subjects with hyperuricemia and ischemic heart disease - the effect of febuxostat on vascular endothelial function in subjects with hyperuricemia and ischemic heart disease
ational Cerebral and Cardiovascular Center.0 个研究点目标入组 62 人开始时间: 2013年11月19日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 62
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1.patients with a history of hypersensitivity to febuxostat. 2.patients with AST or ALT level over than the twice the facilitie standard value. 3.patients with severe renal dysfunction(eGFR under 15 mL/min./1.73m2 or hemodialysis patients). 4.patients received the uric acid descent medicine within two weeks before competent judgment. 5.patients within 1weeks from onset of acute myocardial infarction. 6.patients underwent CABG and after radial artery graft excision. 7. patients with malignant tumor or past history of malignant tumor (except patients with no recurrence or who didn't need specialized treatment for malignant tumor within 5 recent years). 8.patients who take mercaptopurine hydrate ,azathioprine,pyrazinamide or ethambutol. 9.patients participated to other clinical trials within recent 6 months. 10.patients judged not to be suitable as a subject by attending doctor. Especially, patients with serum uric acid level over 9mg/dl should be considered about not to participate to this trial.
研究者
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