Clinico-demographic Profile of the Patient With Pancreaticobiliary Malignancy Undergoing ERCP in a Tertiary Care Center of Nepal

Completed

• Conditions: Cholangiocarcinoma; Bile Duct Carcinoma; Endoscopic Retrograde Cholangio-Pancreatography; Pancreatic Neoplasms

• Registration Number: NCT06888401
• Lead Sponsor: Kathmandu University School of Medical Sciences

Brief Summary

Background Pancreaticobiliary malignancy (PBM) is a group of cancers affecting pancreas and bile duct. The diagnosis is often late and with fatal outcomes. Here, investigators study the clinicodemographic profile of the patients with suspected PBM undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) at a tertiary care center in Nepal.

Material and Methods Retrospectively, a descriptive cross-sectional study was conducted at the endoscopy unit of the Internal medicine department of Dhulikhel Hospital-Kathmandu University Hospital (DH-KUH) from Jan 2017 to Jan 2023. Patients over 18 years of age with suspected PBM with complete medical records who underwent ERCP were included in our study. The descriptive and correlation statistics were done.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-01-01
• Primary Completion: 2023-01-01
• Study Completion: 2023-03-01
• Status Verified: 2025-03
• Study First Submitted: 2025-03-11
• Study First Submitted QC: 2025-03-20
• Last Update Submitted: 2025-03-20
• Study First Posted: 2025-03-21
• Last Update Posted: 2025-03-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 597

Inclusion Criteria

• above 18years of age.
• those with confirmed pancreaticobiliary malignancies, diagnosed through histopathology from ERCP, or Endoscopic Ultrasound (EUS), or Computerized tomography (CT) guided biopsy, and who underwent ERCP
• those with strong suspicions of malignancy confirmed by clinical, CT scan and ERCP findings, and who also underwent ERCP

Exclusion Criteria

• those with suspected intrahepatic cholangiocarcinoma, who underwent percutaneous transhepatic cholangiography with biliary drainage
• Those with incomplete hospital records

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Measurement of risk factors in patients with Pancreaticobiliary Malignancy	6 years from January 2017 to January 2023.	The risk factors will be assessed on the basis of physiological parameters like age, dietary habits, smoking and alcohol habits and comorbities.
Measurement of clinical patterns in patients with Pancreaticobiliary Malignancy	6 years from January 2017 to January 2023.	The clinical patterns will be assessed on the basis of data collected from self-structured proforma that was used as research tool for data collection based on literature review. The patient information was obtained from hospital records after informed consent.
Measurement of treatment modalities in patients with Pancreaticobiliary Malignancy	6 years from January 2017 to January 2023.	The treatment modalities will be assessed with a self-structured proforma which will include the type of treatment modalities like surgical or medical or combined, and the the choice of stent type and technical success of type of stents.

Trial Locations

Locations (1)

Kathmandu University School of Medical Sciences; 🇳🇵 Dhulikhel, Bagmati, Nepal