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A Clinical Study in Children and Adolescents With Mild to Moderate Atopic Dermatitis

Phase 4
Completed
Conditions
Mild to Moderate Atopic Dermatitis
Interventions
Device: Zarzenda
Registration Number
NCT00568412
Lead Sponsor
Bayer
Brief Summary

To show therapeutic efficacy of Zarzenda cream compared to Elidel cream in children and adolescents with mild to moderate atopic dermatitis

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
80
Inclusion Criteria
  • male and female children and adolescents (aged 2 - 17)
  • mild to moderate atopic dermatitis
  • patients in whom a treatment with topical corticosteroids in not recommended or possible
  • wash out periods to be observed
Exclusion Criteria
  • known allergy to one of the two treatments
  • known immunodeficiency
  • known hepatic or renal insufficiency
  • acute skin infections

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1ZarzendaZarzenda applied topically twice daily for three weeks
2ElidelElidel 1% cream, applied topically twice daily for three weeks
Primary Outcome Measures
NameTimeMethod
Investigator's Global AssessmentEnd of study compared to baseline
Secondary Outcome Measures
NameTimeMethod
Affected body surface areaEnd of study compared to baseline
Children's Dermatological Life Quality IndexEnd of study compared to baseline
EASIEnd of study compared to baseline
Patient's assessment of itch, quality of sleep, and global assessmentEnd of study compared to baseline

Trial Locations

Locations (1)

Klinik und Poliklinik fuer Dermatologie, Universtitaetsklinikum

🇩🇪

Bonn, Germany

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