Cold preservation of corneal tissue removed during laser correction of short sight
- Conditions
- Health Condition 1: null- Healthy patients with hypermetropia with amblyopia or aphakia
- Registration Number
- CTRI/2014/01/004331
- Lead Sponsor
- ethradhama Research Foundation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 10
1.HYPERMETROPIA ( > 3D SPHERICAL EQUIVALENT) WITH AMBLYOPIA
2. APHAKIA
3. AGE ABOVE 21 YEARS AND LESS THAN 65 YEARS.
4.ABILITY TO UNDERSTAND AND WILLINGNESS TO SIGN INFORMED CONSENT
5. WILLINGNESS TO PARTICIPATE IN FOLLOW UP VISITS
•EVIDENCE OF OCULAR DISEASES LIKE SEVERE MEIBOMIAN GLAND DISEASES, HERPETIC KERATITIS, UVIETIS, GLAUCOMA.
•VISUALLY SIGNIFICANT CATARACT, RETINAL DISEASES LIKE RETINAL DYSTROPHIES OR DIABETIC RETINOPATHY.
•CYLINDRICAL POWER >1D.
•ANY PATHOLOGIES OF CORNEA LIKE CORNEAL DYSTROPHIES , KERATOCONUS,ANY H/O CORNEAL TRAUMA OR SURGERY WITHIN FLAP ZONE
•DRY EYE STATUS-SCHIRMERâ??S 2 TEST VALUE LESS THAN 10 MM
•LONG TERM OCULAR MEDICATION LIKE Î? BLOCKERS.
•TAKING ANY SYSTEMIC MEDICATION LIKELY TO AFFECT WOUND HEALING LIKE CORTICOSTEROIDS OR ANTIMETABOLITES.
•H/O IMMUNOCOMPROMISED STATE OR PREGNANCY OR NURSING MOTHERS .
•PATIENTS WITH UNREALISTIC EXPECTATIONS.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Safety and refractive outcome of tissue addition (cryopreserved donor lenticule ) in the treatment of hypermetropia and aphakiaTimepoint: patients will be followed up at 1st day, 15th day, 1 month, 3 month and 6 months after surgery
- Secondary Outcome Measures
Name Time Method refractive and clinical outcomes - uncorrected and best corrected visual acuity, contrast sensitivity, aberrations , endothelial changes , topographic changesTimepoint: 1 day, 15th day, 1 month, 3 month, amd 6 month after surgery