NCT00896714已完成不适用
Impact of Environmental and Demographic Factors on Pre-operative Doses of Anesthetic Agents (Prospective Multicenter Study)
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Hopital Foch
- 入组人数
- 3,278
- 试验地点
- 8
- 主要终点
- The dose of propofol required to maintain BIS (bispectral index) between 40 and 60 during maintenance of anesthesia
研究概览
简要总结
The main objective of the study is to analyze the influence of several environmental (i.e., timing: seasonal, circadian) and demographic conditions (i.e., age, gender, menstrual cycle) on anesthetic drug requirements (hypnotic and opiate).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing scheduled surgery under general anesthesia, agreeing to participate in the study
排除标准
- •Age under 18 years
- •Pregnancy, breastfeeding woman
- •Allergy to propofol, soybeans or peanuts
- •Allergy to sufentanil, remifentanil, morphine,
- •Allergy to a muscle relaxant or to any of its excipients
- •Known hypersensitivity to sufentanil, remifentanil, or to other derivates of fentanyl
- •History of central neurological disorder or brain injury
- •Patient with dementia
- •Patient with pacemaker
- •Patient receiving psychotropic drugs or morphine agonist-antagonists
- •Surgery on the skull and/or operating position preventing the use of a bispectral index sensor in suitable conditions
研究组 & 干预措施
Closed loop anesthesia
Experimental
干预措施: Closed loop anesthesia (Device)
结局指标
主要结局
The dose of propofol required to maintain BIS (bispectral index) between 40 and 60 during maintenance of anesthesia
时间窗: during anesthesia
次要结局
- Wake up time(intraoperative period)
- Remifentanil dose requirements for maintenance of anesthesia(intraoperative period)
- Remifentanil dose required for anesthesia induction(intraoperative period)
- Propofol and remifentanil requirements according to the surgical technique(post-operative period)
- Analysis of subgroup of patients according to their clinical status(post-operative period)
- Analysis of subgroup of patients according to the surgical approach(post-operative period)
- Analysis of subgroup of patients according to their pathology(post-operative period)
- Propofol dose required for anesthesia induction(intraoperative period)
- Explicit memorisation(post-operative period)
研究者
研究点 (8)
Loading locations...
相似试验
已完成
不适用
Study of Socio-demographic Factors, Behaviors and Practices Associated With Infection With SARS-CoV-2 Responsible for COVID-19Covid19NCT04607941Institut Pasteur766,818
已完成
不适用
Research on Aging Project in Iceland: Second StageOsteoporosisAtherosclerosisGlucose AbnormalitiesVascular DimentiaObesityAlzheimer's DiseaseNCT01322568National Institute on Aging (NIA)5,764
已完成
不适用
Influence of Social and Environmental Factors on Women's Reproductive Function in a Maya Community of GuatemalaEarly PregnancyNCT00340782National Institute of Environmental Health Sciences (NIEHS)
Unknown
不适用
Format of Patient Education for Different Sociodemographic GroupsType2 Diabetes MellitusCardiovascular DiseasesNCT02961517University of Leicester200
招募中
不适用
Identification of Risk Factors, Exposomics and Genetic Susceptibility of Melanoma in Children, Adolescents and Young AdultsSpitzoid MelanomaCongenital NeviMelanomaNCT06680323University Hospital Tuebingen200