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A pilot randomized controlled trial comparing the effect of a percutaneous and lipofilling technique in patients with a primary Dupuytren*s contracture with standard fasciectomy surgery on convalescence, contracture correction and recurrence rate.

Completed
Conditions
Dupuytren's contracture
hand diseases
10010761
10040795
Registration Number
NL-OMON31898
Lead Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
80
Inclusion Criteria

- males and females
- all ages
- primary Dupuytren*s contracture
- PIP > 30º/ MCP > 20º
- one or more affected rays
- severe or less severe diatheses
- American society of Anaesthesiologists (ASA) criteria I, II and III

Exclusion Criteria

- recurrent Dupuytren*s contracture
- history of hand surgery on the affected finger(s)
- use of blood thinners that can not be stopped for surgery
- ASA IV and V

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>- Convalescence: return to function and return to work<br /><br>- VAS score: standardized list of questions about pain and well-being of the<br /><br>patient; to register the pain of the hand and donor site.<br /><br>- Contracture reductions:<br /><br>1) Total passive extension deficity (TPED): the sum of the passive extension<br /><br>deficits of the metacarpophalangeal, proximal interphalangeal, and distal<br /><br>interphalangeal joints.<br /><br>2) Boyes measure: measuring the distance from pulp to distal palmar crease with<br /><br>the hand in a maximum fist position. Flexion is defined as reduced if the<br /><br>distance is more than 1.5 cm.</p><br>
Secondary Outcome Measures
NameTimeMethod
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