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Eribulin Use for the Treatment of Advanced Breast Cancer: A Prospective Observational Registry

Completed
Conditions
Breast Cancer
Registration Number
NCT02443428
Lead Sponsor
Eisai Limited
Brief Summary

The purpose of this prospective observational registry is to monitor safety of eribulin in routine clinical practice. Additionally, this study will also assess the effectiveness of eribulin in real-life settings.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
77
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Number of participants with adverse events (AEs) and serious adverse events (SAEs)From date of first administration of study drug up to 30 days after last administration of study drug or until approximately 2 years

Safety assessment will consist of monitoring of all AEs, including SAEs at every visit. All participants will be evaluable for safety from the time of their first treatment with eribulin.

Secondary Outcome Measures
NameTimeMethod
Tumour responseFrom date of enrollment, Day 1 and Day 8 of every 21 day cycle or up to approximately 2 years
Overall survival (OS)From date of first administration of study drug to date of death or up to approximately 2 years
Demographic and clinical characteristicsUp to approximately 2 years
Duration of treatmentHistorical data collected at Baseline
Incidence of dose delaysFrom date of first administration up to approximately 2 years
Incidence of dose reductionsFrom date of first administration up to approximately 2 years
Relative dose intensity (RDI) of eribulinFrom date of first administration up to approximately 2 years
Treatment patterns for locally advanced or metastatic breast cancerHistorical data collected at Baseline
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