Soluble CD14 subtype (presepsin) levels in the scheduled high-risk surgery patients who candidates ICU admission ; a prospective observational study
Not Applicable
- Conditions
- the scheduled high-risk surgery patients
- Registration Number
- JPRN-UMIN000013748
- Lead Sponsor
- Fujita Health University School of Medicine Department of Anesthesiology and Critical Care Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
Not provided
Exclusion Criteria
(1)Predict infectious disease before surgery. (2)Emergency surgical patients. (3)Patients who are judged as inappropriate candidates for the trial by the investigators on preoperative anesthetic consultation. (4)Patients who are exposed to infection factor during the operation.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To verify that the level of presepsin and procalcitonin (PCT) in candidates for admission to ICU could not be changed by the high-risk operation.
- Secondary Outcome Measures
Name Time Method (1) Evaluation of presepsin and PCT levels differ depending on operative procedure (Operative methods or cardiopulmonary bypass surgery). (2) Evaluation of presepsin and PCT levels according to severity of the disease in ICU patients. (3) Study of an influencing factor of level of presepsin and PCT. (4) Relationship between survival rate (at Day 28, 60, 90) and levels of presepsin and PCT. (5) The time course of changes in presepsin and PCT levels.