CTRI/2020/02/023195
Completed
Phase 4
Effect of Sodium-glucose Co-Transporter 2 (SGLT2) inhibitors of Left Ventricular Mass and Diastolic Function in Type-2 Diabetes Mellitus Patients at a Tertiary Care Hospital in South India.
izams Institute of Medical Sciences0 sites0 target enrollmentTBD
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Health Condition 1: E119- Type 2 diabetes mellitus without complications
- Sponsor
- izams Institute of Medical Sciences
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\)Patients aged between 18 and 65 years of either sex.
- •2\)Type 2 Diabetes Mellitus Patients with HbA1c \>\=7% \<\= 10%.
- •3\. patients asymptomatic and without history of CVD.
- •4\)Patients on stable dose of tablet metformin (1000\-2500mg) plus any 2 of the folloowing durg combinations\- tablet glimiperide (2\-8mg), tablet gliclazide SR 30\-80 mg, tablet linagliptin 5mg, tablet sitaglyptin 100mg, tablet vildagliptin 50mg, tablet tenaligliptin 20mg since last 3 months.
- •5\)Patients who are SGLT2 inhibitor naïve.
Exclusion Criteria
- •1\)Patients on insulin and GLP\-1 analogues
- •2\)Patients with h/o type 1 Diabetes Mellitus, Congestive Cardiac Failure, Myocardial Infarction, Renal \& Hepatic impairment.
- •3\)Pregnant women and lactating mothers
- •4\)Patients not willing to give informed consent and comply with study related procedures.
Outcomes
Primary Outcomes
Not specified
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