Multicentre, randomised, double-blind trial comparing yellow fever vaccines from 17D and WHO 17DD-213/77 substrains in childre

Not Applicable

Completed

• Conditions: Yellow fever; Infections and Infestations

• Registration Number: ISRCTN72367932
• Lead Sponsor: Bio-Manguinhos (Brazil)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-02-03
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 3500

Inclusion Criteria

Children aged between 9 and 23 months, brought by their guardians to public health care units in regions where vaccination against yellow fever is recommended by the Brazilian National Program of Immunisation

Exclusion Criteria

1. Severe malnutrition
2. Transitory or permanent immunodeficiency
3. Treatment with immunoglobulin or blood products
4. Administration of experimental drugs or vaccines in the previous 60 days or next 60 days of yellow fever vaccination
5. Hypersensitivity to chicken egg products or gelatin
6. Chronic or acute conditions constituting temporary contraindications to routine
7. Immunisation
8. Fever above 37.5°C
9. Mothers unwilling or unable to return 30 days after vaccination for blood collection

Study & Design

• Study Type: Interventional
• Study Design: Not specified