Assessment of Osteosarcopenia Frailty and Cognitive status in Elderly with Hip Fractures: A Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- 1 To determine the prevalence of osteosarcopenia in elderly patients (more than or equal to 60 years) presenting with hip fracture and compare it with elderly presenting with other complaints
研究概览
简要总结
This study aims to assess the prevalence and clinical impact of osteosarcopenia, frailty, and cognitive impairment in elderly patients (more than or equal to 60 years) presenting with hip fractures at AIIMS, New Delhi. It is a comparative cross-sectional and prospective cohort study enrolling 66 hip fracture patients.
Each participant will undergo detailed geriatric assessment including frailty (CFS), cognition (IQCODE), delirium (CAM), nutritional status (MNASF), and evaluation for sarcopenia using handgrip strength, DEXA, and CT-based psoas muscle index. In surgical patients, muscle biopsy of the vastus lateralis will be analyzed histologically to correlate structural muscle changes with clinical sarcopenia. Bone density will be assessed by DEXA to identify osteopenia/osteoporosis.
Participants will be followed for 6 months post surgery to evaluate outcomes including functional recovery (Modified Harris Hip Score, Timed Up and Go test) and mortality.
The study seeks to generate Indian data on osteosarcopenia and frailty in geriatric hip fractures and to determine how these syndromes influence recovery and outcomes, guiding development of integrated orthogeriatric care strategies for elderly fracture patients.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 60.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Age more than or equal to 60 years.
- •Hip fracture diagnosed on X Ray Consent to participate in the study Walking patients prior to fracture, with or without support.
排除标准
- •Pathological fractures (malignancy related) Patients with terminal illnesses (end stage malignancy, severe chronic lung disease or heart failure) Patients with severe cognitive impairment precluding assessment.
- •Polytrauma patients involving more than or equal to 2 systems Those who did not give consent for the study.
结局指标
主要结局
1 To determine the prevalence of osteosarcopenia in elderly patients (more than or equal to 60 years) presenting with hip fracture and compare it with elderly presenting with other complaints
时间窗: 1 Prevalence will be assessed at the baseline | 2 Outcomes will be assessed at 4 weeks and 6 months
2 To evaluate the association of osteosarcopenia, frailty, and nutritional status with clinical outcomes in hip fracture patients over a 6 month follow up period
时间窗: 1 Prevalence will be assessed at the baseline | 2 Outcomes will be assessed at 4 weeks and 6 months
次要结局
- 1. To determine the association between(prevalence of sarcopenia & osteoporosis in)
研究者
Harsh Jain
All India Institute of Medical Sciences