Investigation of the Effects of Anticoagulant/Antiaggregant Use on Postoperative Bleeding Risk in Patients Operated for Bladder Tumor and Benign Prostatic Hyperplasia
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Bezmialem Vakif University
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- Episode of clot retention
Study Overview
Brief Summary
Patients who were using anticoagulant or antiaggregant medications for any reason and underwent transurethral resection of bladder tumor (TUR-BT) or transurethral resection of the prostate (TURP) or open prostatectomy (OP) due to BPH will be compared with those who were not using anticoagulant or antiplatelet medication. The rates of postoperative clot retention, presence of hematuria, reoperation due to hematuria, blood transfusion and re-admissions due to hematuria in the first postoperative month will be compared.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients undergoing complete endoscopic transurethral tumor resection (TUR-BT) for bladder cancer
- •Patients undergoing TURP due to benign prostatic hyperplasia
- •Patients undergoing open prostatectomy due to benign prostatic hyperplasia
Exclusion Criteria
- •Patients who underwent incomplete transurethral tumor resection for bladder cancer
- •Patient who underwent TUR biopsy for restaging with no obvious macroscopic tumoral lesion
- •Patients who underwent cystectomy for bladder cancer
Outcomes
Primary Outcomes
Episode of clot retention
Time Frame: Immediately after the surgery up to 1 month
Presence of clot retention due to hematuria after the operation which requires manuel irrigation
Duration of hospitalization
Time Frame: Immediately after the surgery up to discharge
Duration of hospitalization
Re-operation rates
Time Frame: Immediately after the surgery up to 1 month
Re-operation requirement for hematuria
Rate of re-admission
Time Frame: From discharge up to one month
Rate of re-admission due to hematuria
Requirement of blood transfusion
Time Frame: Immediately after the surgery up to 1 month
Gross hematuria requiring blood transfusion
Secondary Outcomes
- Postoperative hematocrit/hemoglobin levels(Immediately after the surgery up to discharge)
- Amount of irrigation volume(Immediately after the surgery up to discharge)
Investigators
Abdullah İlktaç
Pincipal investigator
Bezmialem Vakif University