Prospective Research for Elderly (≥65 Years Old) Early Breast Cancer Patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- 5-y DFS
研究概览
简要总结
The elderly patients over 65 years old with breast cancer have concomitant diseases, poor tolerance to conventional treatment, and the specific prognosis of breast cancer is relatively good. Previous studies on breast cancer have almost excluded elderly breast cancer patients, and conventional treatment schemes cannot meet the clinical diagnosis and treatment needs of elderly breast cancer patients. The establishment of a prognosis model for elderly breast cancer patients can provide personalized treatment programs. This is important for prolonging the survival time of patients and improving the quality of life. This project plans to observe the relationship between prognosis and pathological staging, molecular typing, and concomitant diseases of elderly breast cancer patients in combination with immune genes, and establish a prognosis model of elderly breast cancer and verify it. This project is expected to establish a new prognostic model for elderly breast cancer patients, accurately judge the prognosis of patients, and provide a new basis for hierarchical and personalized treatment of elderly breast cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 100 Years（Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •female patients with breast cancer
- •≥65 Years Old
- •patients with breast cancer received operation in Peking Union Medical College Hospital
- •treatment regimen was made in Peking Union Medical College Hospital
排除标准
- •patients with metastasis
- •patietns with recurrence
- •patients without pathological information
结局指标
主要结局
5-y DFS
时间窗: 5 year
5-years of disease free survival
5-y BCSS
时间窗: 5 year
5-year of breast cancer-specific survival
次要结局
- 5-y OS(5 year)
- 10-y DFS(10 year)
- 10-y BCSS(10 year)
- 10-y OS(10 year)