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Clinical Trials/NCT05680194
NCT05680194
Recruiting
Not Applicable

Prospective Research for Elderly (≥65 Years Old) Early Breast Cancer Patients

Peking Union Medical College Hospital1 site in 1 country1,000 target enrollmentApril 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Breast Cancer Female
Sponsor
Peking Union Medical College Hospital
Enrollment
1000
Locations
1
Primary Endpoint
5-y DFS
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

The elderly patients over 65 years old with breast cancer have concomitant diseases, poor tolerance to conventional treatment, and the specific prognosis of breast cancer is relatively good. Previous studies on breast cancer have almost excluded elderly breast cancer patients, and conventional treatment schemes cannot meet the clinical diagnosis and treatment needs of elderly breast cancer patients. The establishment of a prognosis model for elderly breast cancer patients can provide personalized treatment programs. This is important for prolonging the survival time of patients and improving the quality of life. This project plans to observe the relationship between prognosis and pathological staging, molecular typing, and concomitant diseases of elderly breast cancer patients in combination with immune genes, and establish a prognosis model of elderly breast cancer and verify it. This project is expected to establish a new prognostic model for elderly breast cancer patients, accurately judge the prognosis of patients, and provide a new basis for hierarchical and personalized treatment of elderly breast cancer.

Registry
clinicaltrials.gov
Start Date
April 1, 2022
End Date
December 1, 2025
Last Updated
3 years ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • female patients with breast cancer
  • ≥65 Years Old
  • patients with breast cancer received operation in Peking Union Medical College Hospital
  • treatment regimen was made in Peking Union Medical College Hospital

Exclusion Criteria

  • patients with metastasis
  • patietns with recurrence
  • patients without pathological information

Outcomes

Primary Outcomes

5-y DFS

Time Frame: 5 year

5-years of disease free survival

5-y BCSS

Time Frame: 5 year

5-year of breast cancer-specific survival

Secondary Outcomes

  • 5-y OS(5 year)
  • 10-y DFS(10 year)
  • 10-y BCSS(10 year)
  • 10-y OS(10 year)

Study Sites (1)

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