Prospective Research for Elderly (≥65 Years Old) Early Breast Cancer Patients

Recruiting

• Conditions: Breast Cancer Female

• Registration Number: NCT05680194
• Lead Sponsor: Peking Union Medical College Hospital

Brief Summary

The elderly patients over 65 years old with breast cancer have concomitant diseases, poor tolerance to conventional treatment, and the specific prognosis of breast cancer is relatively good. Previous studies on breast cancer have almost excluded elderly breast cancer patients, and conventional treatment schemes cannot meet the clinical diagnosis and treatment needs of elderly breast cancer patients. The establishment of a prognosis model for elderly breast cancer patients can provide personalized treatment programs. This is important for prolonging the survival time of patients and improving the quality of life. This project plans to observe the relationship between prognosis and pathological staging, molecular typing, and concomitant diseases of elderly breast cancer patients in combination with immune genes, and establish a prognosis model of elderly breast cancer and verify it. This project is expected to establish a new prognostic model for elderly breast cancer patients, accurately judge the prognosis of patients, and provide a new basis for hierarchical and personalized treatment of elderly breast cancer.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-04-01
• Status Verified: 2022-06
• Study First Submitted: 2022-12-19
• Study First Submitted QC: 2022-12-26
• Last Update Submitted: 2022-12-26
• Study First Posted: 2023-01-11
• Last Update Posted: 2023-01-11
• Primary Completion: 2025-03-31
• Study Completion: 2025-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 1000

Inclusion Criteria

• female patients with breast cancer
• ≥65 Years Old
• patients with breast cancer received operation in Peking Union Medical College Hospital
• treatment regimen was made in Peking Union Medical College Hospital

Exclusion Criteria

• patients with metastasis
• patietns with recurrence
• patients without pathological information

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
5-y DFS	5 year	5-years of disease free survival
5-y BCSS	5 year	5-year of breast cancer-specific survival

Secondary Outcome Measures

Name	Time	Method
5-y OS	5 year	5-year overall survival
10-y DFS	10 year	10-years of disease free survival
10-y BCSS	10 year	10-year of breast cancer-specific survival
10-y OS	10 year	10-year overall survival

Trial Locations

Locations (1)

Peking Union Medical College Hospital; 🇨🇳 Beijing, China