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临床试验/NCT06833775
NCT06833775尚未招募不适用

Evaluation of Neoadjuvant Therapy Efficacy and Postoperative Pathological Indicators in Esophageal Cancer Using CT and Multimodal MRI

Henan Cancer Hospital0 个研究点目标入组 400 人开始时间: 2025年3月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
400
主要终点
CT and multimodal MRI in prediction of neoadjuvant therapy efficacy and postoperative pathological indicators in esophageal cancer

研究概览

简要总结

This study aims to predict the efficacy of different types of neoadjuvant therapy and related postoperative pathological indicators in patients with esophageal cancer based on imaging parameters from CT and multimodal MRI, as well as clinical indicators collected before and after neoadjuvant treatment.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Consecutive patients with histopathological diagnosis of esophageal cancer.
  • Patients underwent neoadjuvant therapy before radical surgery for esophageal cancer: neoadjuvant chemotherapy, neoadjuvant chemoradiotherapy, neoadjuvant chemotherapy plus immunotherapy, neoadjuvant chemoradiotherapy plus immunotherapy.
  • All patients underwent CT and multimodal MRI examinations before and after neoadjuvant therapy.
  • The preoperative clinical data and postoperative pathological data are complete.

排除标准

  • Patients with other primary malignant tumors or previous anti-tumor treatment.
  • CT and MRI images with poor quality.

结局指标

主要结局

CT and multimodal MRI in prediction of neoadjuvant therapy efficacy and postoperative pathological indicators in esophageal cancer

时间窗: March 2025 - January 2030

To evaluate the effectiveness of CT and multimodal MRI in determining the neoadjuvant therapy efficacy and postoperative pathological indicators in esophageal cancer.

次要结局

未报告次要终点

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Qujinrong

Clinical Professor

Henan Cancer Hospital

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