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A Phase 2, Open-Label, Randomized, Parallel Group, Placebo-Controlled, Single-Center Study to Assess Anti-microbial Efficacy and Safety of DCN01 Compared to Unisol® Following Topical Periocular Administration in Healthy Volunteers

Phase 2
Completed
Conditions
Ocular Infection
Interventions
Drug: Unisol
Registration Number
NCT01853722
Lead Sponsor
Deacon Biosciences, Inc.
Brief Summary

This proof-of-concept study evaluates the clinical efficacy and safety of DCN01 in prepping of the periocular region.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
62
Inclusion Criteria
  • Have given a written, informed consent
  • Be willing and able to follow all instructions
  • A negative urine pregnancy test if female of childbearing potential
Exclusion Criteria
  • Known sensitivities to study medication or its components
  • Any signs of an active infection
  • Use of disallowed products during the period indicated prior to the enrollment or during the study
  • Be currently pregnant, nursing, or planning a pregnancy; or be a woman that has a positive pregnancy test
  • Have a condition or a situation which, in the Investigator's opinion, may put the subject at increased risk, confound study data, or interfere significantly with the subject's study participation

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
DCN01DCN01-
UnisolUnisol-
Primary Outcome Measures
NameTimeMethod
Change from baseline in periocular region bacterial loadBaseline to 10 min post dose
Secondary Outcome Measures
NameTimeMethod
Proportion of periocular regions with a reduction from baseline in bacterial load.Baseline to 10 min post dose

Trial Locations

Locations (1)

Andover Eye Associates

🇺🇸

Andover, Massachusetts, United States

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