Evaluation of Effect of Different Ventilator Mods on Atelectasis in Patients Undergoing Laparoscopic Surgery

Not Applicable

Completed

• Conditions: Atelectases, Postoperative Pulmonary; Atelectasis
• Interventions: Procedure: PCV-VG; Procedure: VCV; Diagnostic Test: lung ultrasonography

• Registration Number: NCT03614845
• Lead Sponsor: Derince Training and Research Hospital

Brief Summary

In this study researchers aim to evaluate effect of different ventilation modalities on the developments of atelectasis by using ultrasound.

Detailed Description

Patients undergoing laparoscopic surgery will be randomly assigned either volume controlled ventilation group or pressure controlled volume guaranteed ventilation group. All patients will be performed lung ultrasonography pre and postoperatively to evaluate the development of lung atelectasis and effect of different ventilation modalities on the development of atelectasis.

Study Timeline

• Study First Submitted: 2018-07-22
• Study First Submitted QC: 2018-07-30
• Study First Posted: 2018-08-03
• Study Start: 2018-09-01
• Primary Completion: 2019-09-15
• Study Completion: 2019-09-15
• Status Verified: 2019-11
• Last Update Submitted: 2019-11-25
• Last Update Posted: 2019-11-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• undergoing laparoscopic surgery
• ASA Status I-II

Exclusion Criteria

• Gastroesophageal reflux
• obstructive sleep apnea syndrome
• BMI>30
• severe lung and heart disease
• ASA Status III-IV

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
PCV-VG- Lung Ultrasonography	PCV-VG	patients undergoing laparoscopic surgery will be performed pre and postoperatively lung ultrasonography.after induction of anesthesia patients will be supported by mechanical ventilation on pressure controlled volume guaranteed mode
VCV-Lung Ultrasonography	VCV	patients undergoing laparoscopic surgery will be performed pre and postoperatively lung ultrasonography. after induction of anesthesia patients will be supported by mechanical ventilation on volume controlled ventilation mode.
VCV-Lung Ultrasonography	lung ultrasonography	patients undergoing laparoscopic surgery will be performed pre and postoperatively lung ultrasonography. after induction of anesthesia patients will be supported by mechanical ventilation on volume controlled ventilation mode.
PCV-VG- Lung Ultrasonography	lung ultrasonography	patients undergoing laparoscopic surgery will be performed pre and postoperatively lung ultrasonography.after induction of anesthesia patients will be supported by mechanical ventilation on pressure controlled volume guaranteed mode

Primary Outcome Measures

Name	Time	Method
Effect of different ventilation mods on development of peroperative atelectasis	at minute 5 in postoperative care unit	Patients undergoing laparoscopic surgery will be assigned either volume controlled mode or pressure support volume guaranteed mode. After the operation a researcher will perform lung ultrasonography postoperative at minute 5. Researcher will detect 6 region of each lung totally 12 regions . The researcher will record the modified and original lung ultrasonography scores (LUS Score) of the patients. LUS Score is a scoring system to evaluate atelectasis of lung and scores 1-3 points for each region (Min score 0 max score 36)

Secondary Outcome Measures

Name	Time	Method
Effect of different ventilation mods on development of peroperative atelectasis	at minute 30 in postoperative care unit	Patients undergoing laparoscopic surgery will be assigned either volume controlled mode or pressure support volume guaranteed mode. After the operation a researcher will perform lung ultrasonography in postoperative care unit at minute 30. Researcher will detect 6 region of each lung totally 12 regions . The researcher will record the modified and original lung ultrasonography scores (LUS Score) of the patients. LUS Score is a scoring system to evaluate atelectasis of lung and scores 1-3 points for each region.(Min score 0 max score 36)

Trial Locations

Locations (2)

Marmara University School of Medicine; 🇹🇷 Istanbul, Turkey

Derince Research and Training Hospital; 🇹🇷 Kocaeli, Turkey