the Effectiveness of 3rd Occipital Radiofrequency Versus Systemic Steroid in Headache Management in Rheumatoid Arthritis

Not Applicable

Completed

• Conditions: Rheumatoid Arthritis; Headache
• Interventions: Drug: Radiofrequency; Drug: Steroids

• Registration Number: NCT03852355
• Lead Sponsor: Assiut University

Brief Summary

Rheumatoid arthritis is a common type of autoimmune arthritis that is characterized by inflammation of the synovial membranes. Even though any joint can be affected by the disease, cervical spine is often affected, and cervical pain is reported by 40-88% of RA patients, Cervical spine involvement is a feature of long-lasting disease, where atlantoaxial impaction with odontoid process vertical subluxation through the foramen magnum being one of the greatest and dangerous complications

Detailed Description

To our knowledge the effectiveness of 3rd occipital nerve blocks in managing chronic upper neck pain, headache in RA patients is not measured yet, so we aimed at assessing the the effectiveness of 3rd occipital nerve blocks in headache management in RA patients who used other medical agents and to compare the results with those of the patients who used only 3rd occipital nerve pulsed radiofrequancy on clinical and radiographic bases.

Study Timeline

• Study First Submitted: 2019-02-22
• Study First Submitted QC: 2019-02-22
• Study Start: 2019-02-25
• Study First Posted: 2019-02-25
• Primary Completion: 2019-09-10
• Study Completion: 2019-10-25
• Status Verified: 2020-07
• Last Update Submitted: 2020-07-23
• Last Update Posted: 2020-07-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• patients suffering from upper neck pain and/or headache due to bilateral 3rd occipital nerve involvement evidenced by magnetic resonance imaging (MRI).

Exclusion Criteria

• disc herniation with radicular pain,
• symptomatic spinal stenosis,
• surgical interventions of the cervical spine within the last 3 months,
• uncontrolled major depression or psychiatric disorders,
• heavy opioid usage

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Radiofrequency	Radiofrequency	bilateral 3rd occipital nerve RF under fluoroscopic guidance
Systemic steroid	Steroids	received systemic steroids oral prednisolone tablet, 10 mg/day.

Primary Outcome Measures

Name	Time	Method
neck disability index score	6 months	maximum score = 50 worst paint , lowest score = no pain

Secondary Outcome Measures

Name	Time	Method
Severity of headache Visual analog scale	6 months	maximum scale= 100 worst paint , lowest scale = no pain

Trial Locations

Locations (1)

Emad Zarief Kamel Said; 🇪🇬 Assiut, Egypt