the Effectiveness of 3rd Occipital Radiofrequency Versus Systemic Steroid in Headache Management in Rheumatoid Arthritis; a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- neck disability index score
研究概览
简要总结
Rheumatoid arthritis is a common type of autoimmune arthritis that is characterized by inflammation of the synovial membranes. Even though any joint can be affected by the disease, cervical spine is often affected, and cervical pain is reported by 40-88% of RA patients, Cervical spine involvement is a feature of long-lasting disease, where atlantoaxial impaction with odontoid process vertical subluxation through the foramen magnum being one of the greatest and dangerous complications
详细描述
To our knowledge the effectiveness of 3rd occipital nerve blocks in managing chronic upper neck pain, headache in RA patients is not measured yet, so we aimed at assessing the the effectiveness of 3rd occipital nerve blocks in headache management in RA patients who used other medical agents and to compare the results with those of the patients who used only 3rd occipital nerve pulsed radiofrequancy on clinical and radiographic bases.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients suffering from upper neck pain and/or headache due to bilateral 3rd occipital nerve involvement evidenced by magnetic resonance imaging (MRI).
排除标准
- •disc herniation with radicular pain,
- •symptomatic spinal stenosis,
- •surgical interventions of the cervical spine within the last 3 months,
- •uncontrolled major depression or psychiatric disorders,
- •heavy opioid usage
研究组 & 干预措施
Radiofrequency
bilateral 3rd occipital nerve RF under fluoroscopic guidance
干预措施: Radiofrequency (Drug)
Systemic steroid
received systemic steroids oral prednisolone tablet, 10 mg/day.
干预措施: Steroids (Drug)
结局指标
主要结局
neck disability index score
时间窗: 6 months
maximum score = 50 worst paint , lowest score = no pain
次要结局
- Severity of headache Visual analog scale(6 months)
研究者
Emad Zarief , MD
Associate professor
Assiut University