Prospective Urban Rural Epidemiology Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 200,000
- 试验地点
- 34
- 主要终点
- incident cardiovascular disease
研究概览
简要总结
To examine the impact of health determinants at the individual (e.g. health related behaviors) and societal level (e.g. environmental factors, health related policy, quality of health systems) on health outcomes (e.g. death, non-communicable disease development) across a range of socioeconomic and health resource settings. Additional components of this study will examine genetic factors for non-communicable diseases. This will be examined both through a cross sectional component, and prospectively (cohort component).
详细描述
- To examine the relationship between societal influences and prevalence of risk factors and chronic noncommunicable diseases. Societal determinants are measured by an index of measures from each of the 4 domains of interest: built environment, food and nutrition policy, psychosocial/socioeconomic factors, and tobacco.
- To examine the relationship between societal determinants and incidence of chronic noncommunicable disease events (e.g. cardiovascular disease, cancer) and on changes in rates of selected risk factors (e.g. smoking)
- To examine the relationship between health related behaviors (e.g. diet, physical activity, smoking, alcohol) and health outcomes (e.g. death, non-communicable diseases)
- The quality of health systems across a diverse range of health resource settings, and how this impacts health outcomes
- Genetic factors for non-communicable diseases
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 35 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •consenting adults between 35-70 years of age
排除标准
- 未提供
结局指标
主要结局
incident cardiovascular disease
时间窗: mean follow up of 10 years
cardiovascular death, stroke, myocardial infarction, heart failure
次要结局
- hypertension(mean follow up of 10 years)
- obesity(mean follow up of 10 years)
- incident cancer(mean follow up of 10 years)
- All Cause Hospitalizations(mean follow up of 10 years)
- All cause and cause specific mortality(mean follow up of 10 years)
- Incident COPD(mean follow up of 10 years)
- Respiratory outcomes(mean follow up of 10 years)
- Kidney disease(mean follow up of 10 years)
- Incident Asthma(mean follow up of 10 years)
- Pneumonia(mean follow up of 10 years)
- incident diabetes(mean follow up of 10 years)
- incident injuries(mean follow up of 10 years)
研究者
Salim Yusuf's office
Executive Director, Population Health Research Institute
Population Health Research Institute