The Lucy Trial: Legitimizing Using Childhood memory rescripting early in the first Year

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 73

Inclusion Criteria

Borderline PD based on the DSM-5 as primary diagnosis (assessed with SCID-II or SCID-5-P) and a score of 20 or above on the Borderline Personality Disorder Severity index (BPDSI).

- Age 18-65

- Ability to understand, read, write and speak Dutch.

Exclusion Criteria

- Alcohol or drug dependence needing clinical detox. (After 3 months of abstinence participation is possible).

- Comorbid psychotic disorder (when > 1 year in full remission inclusion is possible).

- Antisocial personality disorder with a history of physical interpersonal violence in the last two years.

- DSM-5 Bipolar disorder, type 1 (current or past) . If there has been no manic episode the last year patients will be included.

- Acute suicide risk

- IQ < 80

- Schema Therapy of any kind (e.g., individual, group, inpatient, outpatient, day treatment) in the past year.

- Patients should not start with any form of psychological treatment or medication during screening or during the study’s treatment or waitlist period. Medication should be on a stable level for 3 months, if not stopped. (Non-PD focused supportive treatment may be continued during wait and screening, but not during the study treatment and study 1-year follow-up period)

- Not able to plan (group) therapy sessions of 90 minutes and individual sessions of 45-60 minutes once a week during 2 years within the treatment period.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome measure is change in the severity and frequency of the DSM-5 BPD manifestations (BPDSI-IV, total score; Arntz et al., 2003; Giesen-Bloo, Wachters, Schouten, & Arntz, 2010). This outcome measure is frequently used in other studies of ST: Giesen-Bloo et al. (2006), Van Asselt et al. (2008), Nadort et al. (2009), and Wetzelaer et al. (2014). This interview yields dimensional total severity scores, as well as dimensional scores per criterion, and diagnostic status.

Secondary Outcome Measures