A Randomised Clinical Trial To Evaluate The Efficacy Of Shigru Beejadi Ghruta And M D Forte Taila Nasya In The Management Of Anovulation In Polycystic Ovarian Disease PCOD
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- 4.Pain during menses
研究概览
简要总结
Polycystic ovarian syndrome is a common gynecological condition that affects women of reproductive age with its increasing incidence due to sedentary lifestyle, excess intake of junk food and stress.
Incidence of 8-13% in women of reproductive age and upto 70% of cases are undiagnosed1. Anovulation is the cause of infertility in about a third of couples attending infertility clinics and PCOS accounts for 90% of such cases
Women with PCOS have irregular menstrual cycle, androgen excess, insulin resistance, anovulation, hirsutism, acne and infertility.
Modern management of PCOS is targeted to weight reduction in obese, hormonal pills and invasive techniques, which gives only symptomatic relief.
We find these symptoms of PCOS in Ayurveda as Pushpaghni Jataharini, Artavakshaya, Nastartava and Granthibhuta Artava
In this study, polycystic ovarian disease (PCOD) will be considered as main emphasis will be given on treatment for ovulation and other symptoms of PCOS will not be included.
Shigru Beejadi Ghruta will be formed by combination of Shigru Beeja, Jatamamsi, Trikatu and Nagakesara.This combination of drugs may be proven beneficial in providing relief to multiple symptoms present in PCOS
Mundi Dhanyaka Taila which is currently available as M.D Forte Taila from Amruthakala Ayurveda is proved to be beneficial in treating anovulation and other symptoms of PCOS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 21.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.Married women 2.Irregular menses 3.Hyperandrogenism 4.Polycystic ovaries.
排除标准
- •Patients with primary amenorrhea.
- •Endocrinological disorders like Diabetes Mellitus, Thyroid abnormalities, Congenital Adrenal Hyperplasia and Hyperprolactinemia.
- •Chronic systemic diseases which can interfere with the treatment.
- •Any malignancy of Breast or cervical or ovarian origin.
- •5.Patients on oral contraceptive pills, IUCD, injectable contraceptives.
- •USG showing Congenital or Acquired Anatomical defects, Pelvic pathology.
- •7.Pregnant and lactating mothers.
- •8.Those contraindicated for Pratimarsha Nasya.
结局指标
主要结局
4.Pain during menses
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
Objective parameters
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
1.Hirsutism score
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
2.GAGS score scale
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
3.ANSC scoring chart
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
5.Vas Score
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
4.BMI and Weight Reduction, and WHR.
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
6.WaLIDD score
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
Assesed based on subjective and objective parameters
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
Subjective Parameters
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
Quantity of menses
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
2.Duration of bleeding
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
3.Interval between the menstrual cycles
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
7.USG of pelvis for ovarian follicular study, endometrial thickness and to assess ovulation BT once and at the end of the study (3rd M).
时间窗: Follicular study will be done for 3 months to check ovulation | and final assessment will be done on 3rd month of study
次要结局
未报告次要终点
研究者
Pawar Sankirna Appu
Alvas Ayurveda Medical College,Moodbidrie