临床试验/NCT00077077

NCT00077077已完成1 期

A Phase I Study Of The Combination Of Oral DJ-927 And Capecitabine In Patients With Advanced Solid Tumors

Daiichi Sankyo6 个研究点分布在 1 个国家开始时间: 2004年2月最近更新: 2012年5月16日

适应症

试验速览

阶段: 1 期
状态: 已完成
发起方: Daiichi Sankyo
试验地点: 6

研究概览研究设计入排标准研究者研究点记录与标识符相似试验

研究概览

简要总结

RATIONALE: Drugs used in chemotherapy, such as DJ-927 and capecitabine, use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.

PURPOSE: This phase I trial is studying the side effects and best dose of DJ-927 and capecitabine in treating patients with locally advanced or metastatic solid tumors.

详细描述

OBJECTIVES:

Primary

Determine the maximum tolerated dose of DJ-927 and capecitabine in patients with locally advanced or metastatic solid tumors.
Determine the dose-limiting and non-dose-limiting toxic effects of this regimen in these patients.

Secondary

Determine the toxicity profile of this regimen in these patients.
Determine the possible pharmacokinetic interactions of this regimen in these patients.
Determine the antitumor activity of this regimen in these patients.

研究设计

研究类型: Interventional
主要目的: Treatment
盲法: None

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

未提供

排除标准

未提供

研究者

发起方

Daiichi Sankyo

申办方类型

Industry

责任方

Sponsor

研究点 (6)

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