NL-OMON52342招募中不适用
Preservation and Transfer of Hepatitis B Virus Immunity after Non-Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation in Adult Sickle Cell Disease Patients (Protect Study). - Preservation and Transfer of HBV Immunity after HSCT for SCD.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 42
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 16 至 64（—）
入选标准
- •- Age 16 years or older
- •- High performance liquid chromatography (HPLC) confirmed diagnosis of SCD (not
- •applicable to participating donors).
- •- An indication for and a planned matched sibling or haploidentical donor
- •non-myeloablative HSCT at the Amsterdam UMC, location AMC (not applicable to
- •patients in cohort 2 (control group) and participating donors)
- •- Written informed consent
排除标准
- •- History of either cleared, chronic or active HBV infection (positive HBsAg,
- •anti-HBs, anti-HBc and/or HBV DNA)
- •- History of auto-immune diseases and/or use of immunosuppressive drugs
- •- History of HIV infection
- •- Known hypersensitivity to yeast of any vaccine constituent
- •- Donor with a history of HBV infection
研究者
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Preservation and Transfer of Hepatitis B Virus Immunity after Non-Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation in Adult Sickle Cell Disease Patients.Sickle cell diseaseNL-OMON23265Amsterdam UMC24
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