To see if Telmisartan helps to improve the symtoms of Raynauds Phenomena (discoloration/pain in fingers on exposure to cold temperatures) in patients of Systemic sclerosis or MCTD
Phase 2
- Conditions
- Health Condition 1: M358- Other specified systemic involvement of connective tissueHealth Condition 2: M340- Progressive systemic sclerosis
- Registration Number
- CTRI/2024/07/069866
- Lead Sponsor
- Institute of Medical Sciences Banaras Hindu University Varanasi Uttar Pradesh 221005
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age greater than or equal to 18 years
2.Patients diagnosed as systemic sclerosis or MCTD with history of Raynauds Phenomena
3.Willing to give signed written consent
Exclusion Criteria
1.Any co-existing significant/incapacitating chronic illness
2.Patient with symptomatic CAD
3.Patients on oral or sublingual nitrates
4.Patient who are pregnant or reproductive couples who have intention of pregnancy
5.Patients with known contraindication to either of IPs or SOC
Patient with symptomatic CAD
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in severity and frequency of Raynauds <br/ ><br>Phenomenon after introduction of drug with <br/ ><br>standard of careTimepoint: 0,6 and 12 weeks
- Secondary Outcome Measures
Name Time Method Any untoward effect or hypersensitivityTimepoint: At 1 & 2 weeks