Efficacy of a thumb opponens splint on manual dexterity in patients with Hereditary Motor and Sensory Neuropathy: a pilot study

• Conditions: 10034606; Charcot-Marie-Tooth disease; Hereditary Motor and Sensory Neuropathy

• Registration Number: NL-OMON32255
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

Diagnosis of HMSN confirmed by DNA or electrophysiological study;
Age between 18 and 70 years;
Loss of opposition (kapandji score < 3)
Impaired manual dexterity (Sollerman test score <80)

Exclusion Criteria

Other disabling disorders in the medical history that might influence hand function of the dominant hand;
Difficulty comprehending the Dutch language;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Manual dexterity assessed with the Sollerman hand function test. The Sollerman<br /><br>test consists of 20 unilateral and bilateral subtests, each comprising a task<br /><br>considered to be an activity of daily living. The tasks reflect the most common<br /><br>handgrips used in daily life. The time necessary to perform the task and the<br /><br>quality of movement of the hand are recorded (test administration time 30-60<br /><br>min). </p><br>