The influence of cytokine biomarkers on sciatica

Not Applicable

Completed

• Conditions: Sciatica; Musculoskeletal Diseases

• Registration Number: ISRCTN24557732
• Lead Sponsor: Keele University (UK)

Brief Summary

2015 results presented at EULAR 2015 https://ard.bmj.com/content/74/Suppl_2/629.1

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-10-09
• Study Completion: 2013-03-29
• Last Update Posted: 30 July 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

This study is nested within a larger cohort study (ATLAS study) and patients for this study will be recruited from the ATLAS cohort.

Hence the principal inclusion criteria is:
1. Adults aged 18 years and over who are attending an ATLAS clinic because they have consulted their GP with low back
2. Leg pain of any duration and who consent and are eligible to take part in the ATLAS study
3. Male & female participants

Exclusion Criteria

Ineligibility and/or not consenting to take part in the ATLAS study. All participants for this study will be recruited from the ATLAS study hence the exclusion criteria to take part in this study are the same as the exclusion criteria for the ATLAS study:
1. Persons with signs and symptoms indicative of possible serious spinal pathology
2. Serious comorbidity which stop patients from being able to undergo the assessment
3. Patients with serious mental health problems who are vulnerable and for whom participation in the study would be detrimental (at the GP?s discretion)
4. Previous spinal surgery
5. Pregnancy
6. Currently receiving physiotherapy (or osteopathy, chiropractic) or under a secondary care consultant for the same problem
7. Not able to read and speak English

Study & Design

• Study Type: Observational
• Study Design: Not specified